Competitive Inhibitor
- resembles shape of substrate closely
- competes with substrate for active site
- binds to active site either reversibly or irreversibly
- prevents substrate from binding to enzyme active site, reducing rate of reaction
Non-competitive Inhibitor
- has a different structure from substrate
- binds to an allosteric site, causing a change in the shape of active site
- substrates can no longer bind to the active site and no enzyme-substrate complex can be formed
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